DNQX Disodium( —— )

Catalog No. M21938 CAS No. 1312992-24-7

DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

DNQX Disodium
Note

Research use only, not for human use.
Brief Description

DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor.
Description

DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor.
In Vitro

DNQX (FG 9041) disodium salt selectively depolarizes thalamic reticular nucleus (TRN) neurons.
In Vivo

DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

non-NMDA
Research Area

——
Indication

——

Chemical Information

CAS Number

1312992-24-7
Formula Weight

296.1
Molecular Formula

C8H2N4Na2O6
Purity

>98% (HPLC)
Solubility

——
SMILES

[Na+].[Na+].[O-]c1nc2cc(c(cc2nc1[O-])[N+]([O-])=O)[N+]([O-])=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lee S H , Govindaiah G , Cox C L . Selective Excitatory Actions of DNQX and CNQX in Rat Thalamic Neurons[J]. Journal of Neurophysiology, 2010, 103(4):1728-1734.

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